Engineered Amine Oxidase for Efficient Oxidative Dehydroaromatization of 1,2,3,4-Tetrahydroquinolines toward Quinolines in Aqueous Media

The oxidative dehydroaromatization (ODA) of 1,2,3,4-tetrahydroquinoline (THQ) is a highly atom economic route for the synthesis of quinoline, a privileged N-heterocyclic motif in pharmaceutical industries, while requiring stoichiometric strong oxidants...