99% of patients with NAFLD meet MASLD criteria and natural history is therefore identical

As part of the background to the recent nomenclature change of non-alcoholic fatty liver disease (NAFLD) to metabolic dysfunction-associated steatotic liver disease (MASLD), a “positive” diagnosis was desired.1,2 This eventually resulted in a requirement that for the MASLD diagnosis to be made, there has to be liver steatosis together with at least one out of five cardiometabolic criteria, e.g. presence of impaired glucose regulation, type 2 diabetes, overweight or obesity, hypertension or dyslipidemia.