芳构化
化学
苯胺
戒指(化学)
胺化
催化作用
组合化学
歧管(流体力学)
有机化学
工程类
机械工程
作者
Peng Yuan,Ronghui Liu,Hai‐Liang Zhu,Zhi‐Xin Liao,Jia‐Chen Xiang,Yan‐Dong Wu
摘要
The precise aromatization of the C-ring of podophyllotoxone to access value-added dehydropodophyllotoxin derivatives conventionally requires the use of equivalent amounts of unsustainable oxidants and suffers from inefficiencies. Taking advantage of the hydridic character of the C8 and C8' of podophyllotoxone, we have developed an I2-DMSO catalytic manifold that enables a green and selective dehydrogenative aromatization to overcome these synthetic challenges. An unprecedented dehydrogenative amination of podophyllotoxone derivatives was also realized using aniline as the reaction partner.
科研通智能强力驱动
Strongly Powered by AbleSci AI