Multidrug-resistant Streptococcus pneumoniae in young children

Multidrug-resistant Streptococcus pneumoniae (S pneumoniae) is one of the major causes of difficult-to-treat pneumococcal disease in young children. Prevalence of the pneumococcal disease has been declining globally after the introduction of the PCV13 pneumococcal conjugate vaccine.1 Lo and colleagues2 reported that the global dissemination of S pneumoniae serotype 24F lineage GPSC10 (CC230) was multidrug-resistant, which is a challenge for serotype-based vaccine strategy. The prevalence of serotype 24F lineage GPSC10 in Europe and the USA is well known, but has not been reported in any countries in Asia.