Advances in Studies on the Rupestonic Acid Derivatives as Anti-influenza Agents

Rupestonic acid (isolated from the Chinese traditional medicine Artemisia rupestris L.) is a sesquiterpene with multifunctional groups and possess higher activity against influenza virus B. In order to improve the biological activity of rupestonic acid, many derivatives have been synthesized and their anti-influenza activity was screened. This review describes the rupestonic acid derivatives and their anti-influenza activity studied by our researching group.