清晨好,您是今天最早来到科研通的研友!由于当前在线用户较少,发布求助请尽量完整的填写文献信息,科研通机器人24小时在线,伴您科研之路漫漫前行!

Survival Predictors in Acute Respiratory Distress Syndrome With Extracorporeal Membrane Oxygenation

医学 急性呼吸窘迫综合征 体外膜肺氧合 机械通风 器官功能障碍 充氧 呼吸衰竭 存活率 死亡率 呼吸窘迫 回顾性队列研究 通风(建筑) 麻醉 外科 内科学 败血症 工程类 机械工程
作者
Li‐Chung Chiu,Feng‐Chun Tsai,Han‐Chung Hu,Chih‐Hao Chang,Cheng‐Chieh Hung,Chung-Shu Lee,Shih‐Hong Li,Shih‐Wei Lin,Lifu Li,Chung-Chi Huang,Ning‐Hung Chen,Cheng‐Ta Yang,Yung‐Chang Chen,Kuo‐Chin Kao
出处
期刊:The Annals of Thoracic Surgery [Elsevier]
卷期号:99 (1): 243-250 被引量:43
标识
DOI:10.1016/j.athoracsur.2014.07.064
摘要

BackgroundExtracorporeal membrane oxygenation (ECMO) can be used as a salvage therapy, but the effectiveness is controversial. The aim of this study was to investigate the predictors of mortality and the influence of organ dysfunction scores in severe acute respiratory distress syndrome (ARDS) patients treated with ECMO.MethodsThe records of adult severe ARDS patients receiving ECMO support from May 2006 to December 2011 at Chang Gung Memorial Hospital were retrospectively analyzed.ResultsThe records of 65 patients with severe ARDS who received venovenous ECMO were analyzed. The hospital survival rate was 47.7%. Survivors were younger than nonsurvivors (41.4 ± 15.4 versus 54.1 ± 16.9 years, respectively; p = 0.002) and had shorter duration of mechanical ventilation before ECMO (52.7 ± 51.1 versus 112.1 ± 101.0 hours, respectively; p = 0.01). Before ECMO, Acute Physiology and Chronic Health Evaluation II, Sequential Organ Failure Assessment, and Multiple Organ Dysfunction scores were significantly lower for survivors than for nonsurvivors. Mortality rate increased with rising predictive score. During 7 days of ECMO use, organ dysfunction scores were significantly lower for survivors than nonsurvivors.ConclusionsSevere ARDS patients who are younger, have shorter duration of mechanical ventilation, and lower organ dysfunction scores before ECMO initiation have more favorable survival outcome. Early application of ECMO, especially if predictive score is below 2, may improve survival. Organ dysfunction scores before and during ECMO support are correlated with survival. Extracorporeal membrane oxygenation (ECMO) can be used as a salvage therapy, but the effectiveness is controversial. The aim of this study was to investigate the predictors of mortality and the influence of organ dysfunction scores in severe acute respiratory distress syndrome (ARDS) patients treated with ECMO. The records of adult severe ARDS patients receiving ECMO support from May 2006 to December 2011 at Chang Gung Memorial Hospital were retrospectively analyzed. The records of 65 patients with severe ARDS who received venovenous ECMO were analyzed. The hospital survival rate was 47.7%. Survivors were younger than nonsurvivors (41.4 ± 15.4 versus 54.1 ± 16.9 years, respectively; p = 0.002) and had shorter duration of mechanical ventilation before ECMO (52.7 ± 51.1 versus 112.1 ± 101.0 hours, respectively; p = 0.01). Before ECMO, Acute Physiology and Chronic Health Evaluation II, Sequential Organ Failure Assessment, and Multiple Organ Dysfunction scores were significantly lower for survivors than for nonsurvivors. Mortality rate increased with rising predictive score. During 7 days of ECMO use, organ dysfunction scores were significantly lower for survivors than nonsurvivors. Severe ARDS patients who are younger, have shorter duration of mechanical ventilation, and lower organ dysfunction scores before ECMO initiation have more favorable survival outcome. Early application of ECMO, especially if predictive score is below 2, may improve survival. Organ dysfunction scores before and during ECMO support are correlated with survival.
最长约 10秒,即可获得该文献文件

科研通智能强力驱动
Strongly Powered by AbleSci AI
更新
大幅提高文件上传限制,最高150M (2024-4-1)

科研通是完全免费的文献互助平台,具备全网最快的应助速度,最高的求助完成率。 对每一个文献求助,科研通都将尽心尽力,给求助人一个满意的交代。
实时播报
路在脚下完成签到 ,获得积分10
1秒前
不爱吃西葫芦完成签到 ,获得积分10
3秒前
天天快乐应助橙100采纳,获得10
8秒前
vikey完成签到 ,获得积分10
15秒前
不回首完成签到 ,获得积分10
18秒前
简洁完成签到 ,获得积分10
21秒前
萧子完成签到 ,获得积分10
32秒前
不打扰完成签到 ,获得积分10
32秒前
ycd完成签到,获得积分10
42秒前
古炮完成签到 ,获得积分10
47秒前
白桃完成签到 ,获得积分10
48秒前
57秒前
科研通AI2S应助科研通管家采纳,获得30
57秒前
59秒前
橙100发布了新的文献求助10
1分钟前
cadcae完成签到,获得积分10
1分钟前
沧海一粟米完成签到 ,获得积分10
1分钟前
chichenglin完成签到 ,获得积分10
1分钟前
宋芽芽u完成签到 ,获得积分10
1分钟前
荔枝小妹完成签到 ,获得积分10
1分钟前
领导范儿应助执着易形采纳,获得30
1分钟前
拼搏山槐完成签到 ,获得积分10
2分钟前
光亮秋天完成签到 ,获得积分10
2分钟前
称心的海蓝完成签到 ,获得积分10
2分钟前
2分钟前
2分钟前
童童应助科研通管家采纳,获得20
2分钟前
rocky15应助科研通管家采纳,获得40
2分钟前
执着易形发布了新的文献求助30
2分钟前
良玉完成签到 ,获得积分10
2分钟前
学习使勇哥进步完成签到 ,获得积分10
3分钟前
王磊完成签到 ,获得积分10
3分钟前
NULI完成签到 ,获得积分10
3分钟前
奈思完成签到 ,获得积分10
4分钟前
困困困完成签到 ,获得积分10
4分钟前
aaa完成签到 ,获得积分10
5分钟前
FUNG完成签到 ,获得积分10
5分钟前
qyyhappy完成签到 ,获得积分10
5分钟前
5分钟前
武雨寒发布了新的文献求助10
5分钟前
高分求助中
Un calendrier babylonien des travaux, des signes et des mois: Séries iqqur îpuš 1036
Sustainable Land Management: Strategies to Cope with the Marginalisation of Agriculture 1000
Corrosion and Oxygen Control 600
Python Programming for Linguistics and Digital Humanities: Applications for Text-Focused Fields 500
Heterocyclic Stilbene and Bibenzyl Derivatives in Liverworts: Distribution, Structures, Total Synthesis and Biological Activity 500
重庆市新能源汽车产业大数据招商指南(两链两图两池两库两平台两清单两报告) 400
Division and square root. Digit-recurrence algorithms and implementations 400
热门求助领域 (近24小时)
化学 材料科学 医学 生物 有机化学 工程类 生物化学 纳米技术 物理 内科学 计算机科学 化学工程 复合材料 遗传学 基因 物理化学 催化作用 电极 光电子学 量子力学
热门帖子
关注 科研通微信公众号,转发送积分 2546022
求助须知:如何正确求助?哪些是违规求助? 2175672
关于积分的说明 5600229
捐赠科研通 1896383
什么是DOI,文献DOI怎么找? 946268
版权声明 565379
科研通“疑难数据库(出版商)”最低求助积分说明 503557