Determination of Astragoloside IV in Xiaoshuantong Granules by HPLC-ELSD

Objective:To determine the content of Astragoloside IV in Xiaoshuantong Granules by HPLC-ELSD. Methods:HPLC- ELSD separation was achieved. Results:The astragaloside Ⅳ showed good linearity (r=0.9999)in the range of 1.08μg-6.48μg, the average recovery was 100.2% with RSD 0.93%. Conclusions:The method is sensitive,reliable,accurate and repeatability,it can be used for quality control method of Xiaoshuantong granules.