A highly selective fluorescent turn-on NIR probe for the bioimaging of hydrogen peroxide in vitro and in vivo

A turn-on NIR fluorescent probe for sensitive detection of hydrogen peroxide was developed. After the addition of hydrogen peroxide, an approximately 15-fold enhancement in fluorescence intensity at 700 nm was observed. The potential of the probe as biosensor for hydrogen peroxide was demonstrated by imaging of hydrogen peroxide in living cells and mice.