In this paper,the experiments of static strength and fatigue have been completed on GH2132 butt weld joint at two different temperatures(360℃ and 410℃).It is shown that the influence of the strain rate on the fracture stress can be neglectable.The S-N curves have also been obtained for two different temperatures.At last,the finite element analysis has been completed to predict the life of GH2132 butt weld joint with the help of S-N curves.The results have shown that the predication life of GH2132 butt weld joint can satisfy the requirement of design.