A study on expression of EGF-R mRNA in the mouse oviduct, uterus and ovary

To examine the activity of EGF-R mRNA in the mouse oviduct、uterus and ovary at the time of ovulation and during days 1 - 5 of pregnancy. The level of EGF-R mRNA activity in the mouse oviduct、 uterus and ovary was measured by RT-PCR technique. A strong ac- tivity of EGF-R mRNA was observed in the oviduct、the uterus and the ovary of the mouse during the whole period studied. The level of expression in the oviduct was lower,in compar- ison with that in the uterus and the ovary. These results suggested that the epidermal growth factor family had effects on the mouse oviduct. uterus and ovary.