Objective:To compare the lipid - regulating effects of fluvastatin and pravastatin. Methods:40 patients in fluvastatin group received 40mg of fluvastatin a day and 38 patients in pravastatin group received 20mg of pravastatin a day. All the two groups were treated for four weeks. Results: The fluvastatin and pravastatin lowered serum total cholesterol by 87 % and 87 % , triglyceride, 60% and 61 % , while they elevated high-density lipoprotein- cholesterol by 65 % and 63 % . Conclusion: Both drugs have similar lipid-regulating effect.