A new form of local connection of girder of electric single-girder crane was designed.The nominal stress and stiffness of new structure was compared with the original structure.The finite element model of girder with different local structure design was established and the impact of local modification on the structural strength was analyzed.The locations and maximum values of structural stress were marked on Mises stress contour plot.The results of Finite element analysis show that the the Mises equivalent stress values of new structure are much lower than the material allowable stress values and further experimental study should be carried out.