5-month- (mature) and 24-month-old (old) male Wag rats were examined for lipid peroxidation products and antioxidant enzymes activity in the liver cytosol. Imbalanced rations are shown to contribute to enhancement of lipid peroxidation entailing accumulation of lipid peroxidation products and inhibition of antioxidant enzymatic activity. Enrichment of food with antioxidant vitamins and fibers leads to lowering of age-related peroxidation.