木质素
纤维素
半纤维素
材料科学
复合数
离子液体
化学工程
共价键
超分子化学
自愈水凝胶
自愈
伤口愈合
复合材料
化学
高分子化学
有机化学
分子
外科
病理
工程类
催化作用
替代医学
医学
作者
Yiwen Zhang,Bo Yuan,Yuqing Zhang,Qiping Cao,Chao Yang,Yao Li,Jinghui Zhou
标识
DOI:10.1016/j.cej.2020.125984
摘要
Trees are made of cellulose, hemicellulose and lignin linked by covalent bonds and supramolecular interactions. Among them, the lignin with three-dimensional structure plays a role in supporting the structure of the tree. Inspired by the nature of the tree, we have designed and synthesized a novel lignin/poly(ionic liquids) composite hydrogel dressing with excellent mechanical strength, self-healing properties, bactericidal activity, and antioxidant activity. This self-healing hydrogel dressing is obtained by the supramolecular interactions between the lignin/poly(ionic liquids) compounds. The introduction of lignin can effectively improve the mechanical properties of the hydrogel dressing. And the bactericidal poly (ionic liquid) modified on the lignin surface through covalent bonds endows this hydrogel dressing good antibacterial activity and self-healing properties. Wound healing model of rats and histomorphological evaluation results suggest that this hydrogel dressing promotes wound healing. Furthermore, the hydrogel dressing still maintains its excellent performances after simple high-temperature disinfection, and can be reused for many times.
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