Vascular formation is a dynamic morphogenic event essential for establishing the circulatory system during embryonic development. The establishment of a vascular network system requires both vasculogenesis and angiogenesis. Vasculogenesis is the formation of blood vessels from endothelial precursor cells, hemangioblasts, whereas angiogenesis is the growth of new vessels through the sprouting of pre-existing vasculature (1–3) .The mechanisms underlying vascular development have been an intriguing problem for biologists and medical scientists alike. These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.