医学
炎症
恶性肿瘤
结节病
银屑病
坏疽性脓皮病
癌症
免疫学
皮肤结节病
免疫系统
肉芽肿
皮肤病科
肉芽肿性炎症
病理
疾病
内科学
作者
Doru T Alexandrescu,Neil H. Riordan,Thomas E. Ichim,Carol A. Kauffman,Filamer D Kabigting,Constance T Dutton,Constantin A Dasanu
摘要
A various array of cutaneous granulomatous disorders have been found to be associated with internal malignancy. Among them, sarcoidosis, granuloma anulare (GA), psoriasis, pyoderma gangrenosum (PG), or other neutrophilic dermatoses such as the Sweet syndrome and subcorneal pustular dermatosis may precede the development of a neoplastic process by months or years. Pathogenic links of inflammation with cancer are discussed, including inflammation, intrinsic immune dysfunction, cytokines and interleukins, angiogenetic factors, and epigenetic changes.
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