Electrospun Antimicrobial Polymeric Nanofibers in Wound Dressings

The efficient wound management highly depends on the dressing materials, which involves the processess of surface protection, anti-inflammation, and antibacterial properties. Due to the inherent porous structure of electrospun nanofibers, various bactericidal agents can be blended to obtain the antimicrobial nanofibrous membranes as wound dressings. The formed polymeric dressings show desirable biocompatibility and vapor permeable property, low cytotoxicity, and enhanced drug delivery at the wound site, which is beneficial for the wound healing. This review mainly summarizes the recent progress of electrospun antimicrobial polymeric nanofibers as wound dressings with a special focus on the incorporation of bactericidal components including antibiotics, metal nanoparticles, plant extract, and biomacromolecule.