Effect of Periodontal Therapy on Salivary Extracellular Vesicle Cargos: An Exploratory Study

This exploratory study demonstrated that NSPT led to clinical improvements accompanied by changes in the composition and cytokine cargo of salivary host EVs. Alterations in salivary host EV sub-populations and cytokine profiles may have potential utility as biomarkers for monitoring treatment outcomes in periodontitis.