Polycationic Open‐Shell Cyclophanes: Synthesis of Electron‐Rich Chiral Macrocycles, and Redox‐Dependent Electronic States

Abstract π‐Conjugated chiral nanorings with intriguing electronic structures and chiroptical properties have attracted considerable interests in synthetic chemistry and materials science. We present the design principles to access new chiral macrocycles ( 1 and 2 ) that are essentially built on the key components of main‐group electron‐donating carbazolyl moieties or the π‐expanded aza[7]helicenes. Both macrocycles show the unique molecular conformations with a ( quasi ) figure‐of‐eight topology as a result of the conjugation patterns of 2,2’,7,7’‐spirobifluorenyl in 1 and triarylamine‐coupled aza[7]helicene‐based building blocks in 2 . This electronic nature of redox‐active, carbazole‐rich backbones enabled these macrocycles to be readily oxidized chemically and electrochemically, leading to the sequential production of a series of positively charged polycationic open‐shell cyclophanes. Their redox‐dependent electronic states of the resulting multispin polyradicals have been characterized by VT‐ESR, UV/Vis‐NIR absorption and spectroelectrochemical measurements. The singlet (Δ E S‐T =−1.29 kcal mol −1 ) and a nearly degenerate singlet‐triplet ground state (Δ E S−T(calcd) =−0.15 kcal mol −1 and Δ E S−T(exp) =0.01 kcal mol −1 ) were proved for diradical dications 1 2+2 ⋅ and 2 2+2 ⋅, respectively. Our work provides an experimental proof for the construction of electron‐donating new chiral nanorings, and more importantly for highly charged polyradicals with potential applications in chirospintronics and organic conductors.