Electrical gas sensors based on metal–organic frameworks for breath diagnosis

The components of human-breathed gas have a direct impact on disease monitoring, and non-invasive breath analysis is a growing area of interest. More than ever, sensors with high sensitivity, excellent selectivity, affordability, and portability are in demand. Metal-organic framework materials (MOFs), which have high porosity, exceptional physical chemistry properties, and designability, as well as potent interactions with gas molecules, make them ideal for use in the sensing field. The various respiratory illness markers are outlined in this review along with the rationale behind MOFs-based electrical gas sensors and their advancements in various disease monitoring. Finally, the difficulties of employing MOFs-based electrical gas sensors for illness monitoring in clinical practice are discussed.