Colorimetric Analysis Utilizing Surface Plasmon Resonance of Nanoparticles

The plasmon resonance LSPR colorimetric sensing based on noble metal nanoparticles has been widely used in many fields such as environment, food safety, and biomedicine due to its advantages of simple operation and low cost. It plays an important role in the detection of important substances such as organic molecules, inorganic ions, DNA, and proteins. In this paper, the principles and applications of two sensing modes based on typical noble metal nanoparticles such as gold nanoparticles, silver nanoparticles, gold nanorods, triangular silver, and gold@silver are summarized: one is LSPR colorimetric sensing based on aggregation; the second is based on the "non aggregation" LSPR sensing caused by etching and growth. At the same time, the response characteristics of noble metal nanoparticles with different chemical composition, size, morphology and surface properties to different analytes were summarized. Aiming at the selectivity problem in colorimetric sensing applications, the construction and use of colorimetric analysis sensor array are briefly introduced. Finally, the problems faced by LSPR colorimetric sensing of nanoparticles are briefly summarized and the research prospects are prospected. In the future, the potential applications of plasma sensors based on noble metal nanoparticles will be further broadened, which will also contribute to the development of simple, sensitive and real-time colorimetric sensing systems.