Effects of quorum sensing deficiency on P.aeruginosa biofilm formation

Objective:To understand the effects of quorum sensing system on P. aeruginosa biofilm formation. Methods:Examination of the biofilm developments of PAO1,lasIrhlI and lasRrhlR mutants in vitro by means of scanning electronic microscopy (SEM) after three days' incubation.Results:After three days' incubation,well developed biofilm was observed in PAO1 group,whereas poor biofilm formation was seen in lasIrhlI and lasRrhlR mutant groups.Conclusion:Quorum sensing system is important in the formation of P.aeruginosa biofilm.