医学
嗜铬粒蛋白A
突触素
阶段(地层学)
子宫颈
免疫组织化学
内科学
子宫颈
癌
胃肠病学
存活率
转移
肿瘤科
妇科
病理
癌症
古生物学
生物
作者
Y Wang,Kuikui Mei,Min Xiang,J M Li,Rui Xie
出处
期刊:PubMed
日期:2013-01-01
卷期号:34 (4): 307-10
被引量:3
摘要
To analyze the clinicopathological data of 13 cases of small cell neuroendocrine carcinoma (SCNEC) of the uterine cervix who received treatment at this medical institutions over the past five years with patient survival as the primary endpoint.The clinicopathologic data of 13 cases were reviewed. Immunohistochemistry was performed using antibodies against synaptophysin and chromogranin A and Ki-67. Survival was analyzed using the Kaplan-Meier method and log-rank tests.The median age of these patients was 37 years (range 21-62). Immunohistochemistry showed that the positive rate of synaptophysin and chromogranin A was 100% (13/13) and 69.23% (9/13), respectively. The median survival of patients with early-Stage I-II SCNEC of the uterine cervix (17.5 months) was significantly higher than that of patients with advanced stage SCNEC of the uterine cervix (four months) (p < 0.05). There was no local recurrence in all 13 patients. Five patients died of distant metastasis in less than six months.SCNEC of the uterine cervix is a highly-malignant disease and early-stage patients showed significantly longer survival compared to late-stage patients. Early diagnosis and prompt combination treatment may improve the outcome of patients with SCNEC of the uterine cervix.
科研通智能强力驱动
Strongly Powered by AbleSci AI