脚手架
组织工程
背景(考古学)
制作
材料科学
聚合物
细胞外基质
纳米技术
天然聚合物
化学
生物医学工程
工程类
复合材料
生物化学
生物
古生物学
替代医学
病理
医学
作者
Somayeh Vandghanooni,Morteza Eskandani
标识
DOI:10.1016/j.ijbiomac.2019.12.249
摘要
Fabrication of an appropriate scaffold is the key fundamental step required for a successful tissue engineering (TE). The artificial scaffold as extracellular matrix in TE has noticeable role in the fate of cells in terms of their attachment, proliferation, differentiation, orientation and movement. In addition, chemical and electrical stimulations affect various behaviors of cells such as polarity and functionality. Therefore, the fabrication approach and materials used for the preparation of scaffold should be more considered. Various synthetic and natural polymers have been used extensively for the preparation of scaffolds. The electrically conductive polymers (ECPs), moreover, have been used in combination with other polymers to apply electric fields (EF) during TE. In this context, composites of natural polypeptides and ECPs can be taken into account as context for the preparation of suitable scaffolds with superior biological and physicochemical features. In this review, we overviewed the simultaneous usage of natural polypeptides and ECPs for the fabrication of scaffolds in TE.
科研通智能强力驱动
Strongly Powered by AbleSci AI