GFP Chromophores from L‐Phenylalanine: Synthesis, Photophysical and Thermal Properties

Abstract Synthesis of π‐conjugated green fluorescent protein chromophores analogs derived from amino acids are established. Indole and p ‐nitrophenyl tethered derivatives as the main structure could improve the thermal stability and optical property of the materials. The chromophores show good solubility in MeOH and CH 3 CN. They also show good thermal stability for practical applications. These compounds showed steady green light emissions in the range of 524–578 nm in solution.