PHYTOCHEMICAL SCREENING AND MICROBIAL ASSESSMENT OF Moringa oleifera SEED CRUDE OIL EXTRACT

The present inherent ability of an organism to human pathogenic infections compelled the need to explore new substances with antimicrobial properties from plant-based materials. Moringa oleifera seed extract was evaluated for antimicrobial effects against the selected bacteria strains - Bacillus subtilis, Klebsiella pneumonia, Staphylococcus aureus, Escherichia coli and Pseudomonas aeruginosa and selected fungi - Rhizopus stolonifera and Candida albicans. The zone of inhibition test revealed samples inhibited microbial growth to various extents with greater sensitivity against fungal as viewed in the bacterial strains. Phytochemical screening of analyzed samples revealed the presence of some metabolites (secondary) such as Alkaloids, saponins, flavonoids, Anthocyanin and betacyanin, Quinones, tannins, Terpenoids and Acids. Gas-chromatography-mass spectrometry (GCMS) analysis identified about 33 chemical components.