偷看
材料科学
血链球菌
生物相容性
锌
石墨烯
涂层
生物膜
复合材料
纳米技术
冶金
聚合物
细菌
遗传学
生物
作者
Shihui Yang,Wanqi Yu,Jingjie Zhang,Xiao Han,Jun-Yan Wang,Duo Sun,Rui-Ning Shi,Yanmin Zhou,Haibo Zhang,Jinghui Zhao
标识
DOI:10.1088/1748-605x/ac51ba
摘要
About 30% failures of implant are caused by peri-implantitis. Subgingival plaque, consisting of S. sanguinis, F. nucleatum,P. gingivalis et al, is the initiating factor of peri-implantitis. Polyetheretherketone (PEEK) is widely used for the fabrication of implant abutment, healing cap and temporary abutment in dental applications. As a biologically inert material, PEEK has shown poor antibacterial properties. To promote the antibacterial activity of PEEK, we loaded ZnO/GO on sulfonated PEEK. We screened out that when mass ratio of ZnO/GO was 4:1, dip-coating time was 25 min, ZnO/GO modified SPEEK shown the best physical and chemical properties. At the meantime, the ZnO/GO-SPEEK samples possess a good biocompatibility. The ZnO/GO-SPEEK inhibitsP. gingivalisobviously, and could exert an antibacterial activity toS. sanguinisin the early stage, prevents biofilm formation effectively. With the favorablein vitroperformances, the modification of PEEK with ZnO/GO is promising for preventing peri-implantitis.
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