Hemorrhagic shock after contrast‐enhanced ultrasound‐guided liver biopsy: A case report of primary hepatic angiosarcoma

Abstract Primary hepatic angiosarcoma (PHA) is a rare, highly aggressive malignancy. There is no specificity in clinical manifestations, laboratory examinations and imaging examinations. The definitive diagnosis of PHA depends on pathological analysis. The gold standard method to obtain specimens is percutaneous transhepatic biopsy under the guidance of contrast‐enhanced ultrasound (CEUS). However, CEUS‐guided biopsy for PHA is controversial. If a biopsy is necessary, a comprehensive preoperative evaluation is essential. In addition, CEUS has an auxiliary value in diagnosing PHA. In this case, we present an elderly woman who underwent CEUS‐guided liver mass biopsy. The patient developed hemorrhagic shock after biopsy.