Subchorionic hematoma volume in the first trimester and risk of spontaneous abortion

"Objective : to establish an association between subchori - onic hematoma volume and risk of spontaneous abortion. Methods : patients with viable intrauterine pregnancy be - tween 6 and 13 weeks were included and with diagnosis of subchorionic hematoma with or without genital bleed - ing and visible heart rate by ultrasound. Patients were divided into two groups depending on the interruption or continuity of pregnancy: patients who presented spon - taneous abortion and patients who continued with their pregnancy after the first trimester. Settings : Maternity “Dr. Armando Castillo Plaza” and Hospital “Dr. Urquinaona”. Maracaibo, Venezuela. Results : Two hundred patients were selected. The gesta - tional age at the moment of the ultrasound evaluation was 9.2 ± 2.0 weeks and the mean value of subchorionic hema - toma volume was 22.4 ± 12.2 cm 3 . The rate of spontaneous abortion in the group was 33.5%. Patients who presented spontaneous abortion did not show significant differences in the maternal age and gestational age at the moment of the ultrasound evaluation compared to those who contin - ued with their pregnancy (p = ns). Patients with spontane - ous abortion presented higher mean values of subchorionic hematoma volume (p = 0.05). Relative risk were significant for groups who presented hematomas considered big (rela - tive risk = 1.74; interval confidence 95%, 1.20 – 2.44) and very big (relative risk = 4.19, interval confidence 95%, 2.51 – 7.02; p < 0.05). Conclusion : There is an association between the first tri - mester subchorionic hematoma volume and an increased risk of spontaneous abortion."