A Therapeutic Link between Astrogliosis and Remyelination in a Mouse Model of Multiple Sclerosis

Injuries to the mammalian CNS often provoke astrogliosis, a process in which reactive astrocytes surround the site of injury to restrict tissue damage ([Voskuhl et al., 2009][1]; [Hamby and Sofroniew, 2010][2]). Formation of the glial scar has historically been viewed as a short-term solution that