缩进
纳米压痕
纳米力学
弹性(物理)
原子力显微镜
弹性模量
变形(气象学)
材料科学
纳米金刚石
接触力学
纳米技术
复合材料
物理
有限元法
热力学
钻石
作者
Yue Cui,Weng-Hang Leong,Chu-Feng Liu,Ke‐Qing Xia,Xi Feng,Csilla Gergely,Ren‐Bao Liu,Quan Li
出处
期刊:Nano Letters
[American Chemical Society]
日期:2022-05-04
卷期号:22 (10): 3889-3896
标识
DOI:10.1021/acs.nanolett.1c05037
摘要
Nanoindentation based on atomic force microscopy (AFM) can measure the elasticity of biomaterials and cells with high spatial resolution and sensitivity, but relating the data to quantitative mechanical properties depends on information on the local contact, which is unclear in most cases. Here, we demonstrate nonlocal deformation sensing on biorelevant soft matters upon AFM indentation by using nitrogen-vacancy centers in nanodiamonds, providing data for studying both the elasticity and capillarity without requiring detailed knowledge about the local contact. Using fixed HeLa cells for demonstration, we show that the apparent elastic moduli of the cells would have been overestimated if the capillarity was not considered. In addition, we observe that both the elastic moduli and the surface tensions are reduced after depolymerization of the actin cytoskeleton in cells. This work demonstrates that the nanodiamond sensing of nonlocal deformation with nanometer precision is particularly suitable for studying mechanics of soft biorelevant materials.
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