Antifungal long-chain alkenyl sulphates isolated from culture broths of the fungus Chaetopsina sp.

Invasive infections caused by fungi have experienced a great increase in recent years, mainly due to the rising number of immunocompromised patients. The therapeutic arsenal of antifungal drugs currently in use is rather limited and the evolving threat of resistant emerging pathogens has turned the development of new antifungal agents, preferably naturally-occurring compounds with novel mechanisms of action, low resistance rates and fewer side effects, into an urgent medical need.