生物降解
微塑料
生化工程
生物可分解塑胶
聚丙烯
塑料废料
细菌
环境科学
化学
生物塑料
聚苯乙烯
微生物
环境化学
制浆造纸工业
废物管理
有机化学
聚合物
生物
工程类
遗传学
作者
Soo‐Jin Yeom,Thien‐Kim Le,Chul‐Ho Yun
标识
DOI:10.1016/j.tibtech.2021.06.003
摘要
Plastic contamination currently threatens a wide variety of ecosystems and presents damaging repercussions and negative consequences for many wildlife species. Sustainable plastic waste management is an important approach to environmental protection and a necessity in the current life cycle of plastics in nature. Plastic biodegradation by microorganisms is a notable possible solution. This opinion article includes a proposal to use hypothetical P450 enzymes with an engineered active site as potent trigger biocatalysts to biodegrade polyethylene (PE) via in-chain hydroxylation into smaller products of linear aliphatic alcohols and alkanoic acids based on cascade enzymatic reactions. Furthermore, we propose the adoption of P450 into plastic-eating synthetic bacteria for PE biodegradation. This strategy can be applicable to other dense plastics, such as polypropylene (PP) and polystyrene (PS).
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