The asymmetric unit of the title compound, C 18 H 10 F 4 N 2 O, is composed of two identical molecules having different configurations. Although both molecules adopt a trans configuration about the N−O bond [C−N−O−C 164.2 (3) and − 162.0 (2)°], substantial twists of all the aromatic rings relative to the C=N−O plane show no correlation between the conformers. Despite the apparently random molecular configurations, the packing arrangement involves several π interactions between adjacent molecules