N-Methyl Morpholine Chlorochromate: An Efficient Reagent for Oxidation of Primary and Secondary Alcohols to Carbonyl Compounds

Abstract Instantaneous generation of N-methyl morpholine chlorochromate (NMMCC) is an efficient reagent for oxidation of primary and secondary alcohols to the corresponding carbonyl compounds. The comparison of reaction time and product yield was studied with novel NMMCC and other chlorochromate reagents and shows that the presented method requires less reaction time with good yield at laboratory temperature. The synthesis of reagent, formation of toxic and hazardous chromylchloride have been avoided, and also use of NMMCC under microwave irradiation for oxidation leads to fast reaction time and success of the strategy. Keywords: Alcoholscarbonyl compoundsmicrowave irradiation N-methyl morpholine chlorochromate (NMMCC)oxidation ACKNOWLEDGMENT The authors are grateful to University Grants Commission, New Delhi, for financial support under UGC Project Order No. DV6/69/UGC/2006-07, University Grant Commission (UGC)-SAP (Phase I) Project Vide No. F. 540/10/DRS/2004–05 (SAP I) for IR data. The instruments granted by the Department of Science and Technology-Fund for Important of Science and Technology (DST-FIST) program to measure the CHNS data are greatly acknowledged. Notes Note. CM = conventional method; MW = microwave method.