体温过低
热疗
医学
冲程(发动机)
缺血
重症监护医学
缺血性中风
神经科学
脑缺血
麻醉
心理学
心脏病学
内科学
机械工程
工程类
作者
Francisco Campos,Miguel Rodríguez Blanco,David Barral,Jesús Agulla,Pedro Ramos‐Cabrer,José Castillo
标识
DOI:10.1016/j.neuint.2012.02.003
摘要
In the last decades, the interest in the association between body temperature and stroke outcome has reemerged, and the use of animal models has made it possible to know the underlying pathogenic mechanisms involved, most of them with pending confirmation in human clinics. In this work, we will review the effects of hyperthermia and hypothermia and its pathogenesis on ischemic stroke, and the evidence of the efficacy and safety of anti-hyperthermic and hypothermic treatments. We will describe how treatment of hyperthermia on ischemic stroke patients, improves patient comfort and outcome, both in the short and the long term, but new clinical studies are needed in this field. Despite the theoretical and experimental bases in favor of hypothermia for the treatment of brain ischemia, there is no definitive clinical evidence that has proved its benefits, so far. With current knowledge, an objective of a body temperature between 35.5 and 36.5 °C seems an optimal therapeutic target for both hyperthermic and normothermic patients.
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