粒体自噬
线粒体
生物
控制(管理)
神经科学
细胞生物学
计算机科学
自噬
遗传学
细胞凋亡
人工智能
作者
Yijin Wang,Peng Ji,Qiuwei Pan
标识
DOI:10.1016/j.tips.2023.06.006
摘要
Mitochondrial quality control (MQC) plays a crucial role in maintaining mitochondrial health. Mitochondrial dynamics and mitophagy are two intricate processes of the MQC machinery acting at the organelle level to orchestrate mitochondrial homeostasis. Here, we discuss how viruses perturb these two processes to facilitate their infections and emphasize the rationale and challenges of therapeutically targeting MQC for treating viral diseases.
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