生物催化
地标
合成生物学
纳米技术
蛋白质工程
计算生物学
化学
生化工程
材料科学
生物
酶
计算机科学
工程类
生物化学
催化作用
人工智能
离子液体
作者
Adam O’Connell,Amber Barry,Ashleigh J. Burke,A. Hutton,Elizabeth L. Bell,Anthony P. Green,Elaine O’Reilly
摘要
Biocatalysis has become an important tool in chemical synthesis, allowing access to complex molecules with high levels of activity and selectivity and with low environmental impact. Key discoveries in protein engineering, bioinformatics, recombinant technology and DNA sequencing have contributed towards the rapid acceleration of the field. This tutorial review explores enzyme engineering strategies and high-throughput screening approaches that have been applied for the discovery and development of enzymes for synthetic application. Landmark developments in the field are discussed and have been carefully selected to highlight the diverse synthetic applications of enzymes within the pharmaceutical, agricultural, food and chemical industries. The design and development of artificial biocatalytic cascades is also examined. This tutorial review will give readers an insight into the landmark discoveries and milestones that have helped shape and grow this branch of catalysis since the discovery of the first enzyme.
科研通智能强力驱动
Strongly Powered by AbleSci AI