What does the TIME study tell us about morning and evening dosing of antihypertensive medication?

Abstract Commentary on: Mackenzie IS, Rogers A, Poulter NR, et al . Cardiovascular outcomes in adults with hypertension with evening vs morning dosing of usual antihypertensives in the UK (TIME study): a prospective, randomised, open-label, blinded-endpoint clinical trial. Lancet . 2022;400:1417–25.