Glucose‐Responsive Insulin Delivery: Microneedle‐Array Patch Fabricated with Enzyme‐Free Polymeric Components Capable of On‐Demand Insulin Delivery (Adv. Funct. Mater. 7/2019)

In article number 1807369, Akira Matsumoto and co-workers report an electronics-free, enzyme-free, and nanoparticle-free smart artificial on-skin pancreas, which is a hybrid microneedle-array patch fabricated with a glucose-sensitive boronate-hydrogel and biocompatible silk fibroin semi-interpenetrating network. This microneedles-array patch could mimic the functionality of the pancreas and provide on-demand insulin delivery in a safe, painless, and convenient way.