Objective To make a preliminary analysis of orthokeratology(OK) for treating myopia Methods OK lenses were chosen to treat myopia with or without astigmatism according to the myopia characterizations, then changes of their visions, refractions, corneal curvature and eccedtricities after being treated for ld, 1、2、3、4 weeks were observed once every 4weeks and were followed up for 18 months Results Significant changes were observed after being treated Slight myopia: the diopters decreased-2 75D±0 50D,the horizontal meridians flattened 1 64±0 21, the vertical 0 92±0 27 and the eccedtricities declined 0 47±0 11; Middle myopia: the diopters decreased -5 50D±0 75D,the horizontal meridians flattened 2 16±0 45, the vertical 1 61±0 67, and the eccedtricities declined 0 38±0 07; High myopia:the diopters did -6 75D±0 50D,the horizontal did 3 86±0 56, the vertical 2 97±0 67 and the eccedtricities did 0 32±0 10 The predicabilities of slight and middle myopia were superior to high myopia's Conclusion Orthokeratology is a non traumatic therapy and the clinical application should be careful and scientific