The vacuum freeze-drying technology is the drying process in particular vacuum-degree and low temperature. Its products have an advantage over the other products that adopt other drying methods. The principle of vacuum freeze-drying and three operational process are introduced. The application of vacuum freeze-drying on flowers is also elaborated. It includes the character of vacuum freeze-drying flowers and the research on vacuum freeze-drying flowers in recent years. Besides the moisture content of Rosa chinensis, Aztec marigola, Limonium bicolor and peony, the eutectic temperature and co-melting temperature of peony are measured. The peony stems, leaves and flowers were examined with scanning electron microscopy( SEM ). The result shows that it is available for fresh flower to adopt the method of vacuum freeze-drying.