Effective Component Selection of Atraotydin Extract against Influenza Virus

Objective To screen the active components against anti influenza virus in Atraotydin. Methods The extracts were separated by supercritical CO2 fluid extraction(SFE-CO2),aqueous extraction and silica column chromatography.Madin-Darby Canine Kidney(MDCK) cell tissue culture was used to screen the effective ingredient with fluenza A virus and influenza B virus. Results Atractylon and the SFE-CO2 Atracylodes Lancea Rhizoma could kill influenza virus;Atractylodin and the water extract from Rhizoma Atractylodis had no effect on influenza virus. Conclusion Atractylon is effective ingredient for anti influenza virus in Atraotydin.