Comparison of the hemolytic activity between Candida albicans and Candida glabrata isolates in oral cavity of HIV-infected patients

Objective To investigate the hemolytic activity of Candida albican and Candida glabrata isolates in oral cavity of HIV-infected patients,and its relationship with the immunity of the patients.Methods Forty Candida albican and 40 Candida glabrata isolates were grouped by infection types and CD4 cell count.The hemolytic activity was measured by sugar-enriched sheep blood agar medium.Results The hemolytic activity of Candida glabrate was significantly higher than that of Candida albicans(P 0.01).Conclusion Hemolytic activity is an important virulence factor of Candida.The hemolytic activity of Candida glabrata was higher than that of Candida albicans in oral cavity of HIV-infected patients.