功能磁共振成像
医学
磁共振成像
认知
血氧水平依赖性
神经科学
生物标志物
神经影像学
心理学
精神科
放射科
生物化学
化学
标识
DOI:10.1016/j.nec.2010.11.001
摘要
Blood Oxygen Level Dependent (BOLD) functional magnetic resonance imaging (fMRI) depicts changes in deoxyhemoglobin concentration consequent to task-induced or spontaneous modulation of neural metabolism. Since its inception in 1990, this method has been widely employed in thousands of studies of cognition for clinical applications such as surgical planning, for monitoring treatment outcomes, and as a biomarker in pharmacologic and training programs. More recently, attention is turning to the use of pattern classification and other statistical methods to draw increasingly complex inferences about cognitive brain states from fMRI data. This article reviews the methods, challenges, and future of fMRI.
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