脚手架
组织工程
材料科学
细胞外基质
纳米技术
再生(生物学)
生物材料
生物医学工程
化学
工程类
细胞生物学
生物化学
生物
作者
Vahideh Raeisdasteh Hokmabad,Soodabeh Davaran,Ali Ramazani,Roya Salehi
标识
DOI:10.1080/09205063.2017.1354674
摘要
Current strategies of tissue engineering are focused on the reconstruction and regeneration of damaged or deformed tissues by grafting of cells with scaffolds and biomolecules. Recently, much interest is given to scaffolds which are based on mimic the extracellular matrix that have induced the formation of new tissues. To return functionality of the organ, the presence of a scaffold is essential as a matrix for cell colonization, migration, growth, differentiation and extracellular matrix deposition, until the tissues are totally restored or regenerated. A wide variety of approaches has been developed either in scaffold materials and production procedures or cell sources and cultivation techniques to regenerate the tissues/organs in tissue engineering applications. This study has been conducted to present an overview of the different scaffold fabrication techniques such as solvent casting and particulate leaching, electrospinning, emulsion freeze-drying, thermally induced phase separation, melt molding and rapid prototyping with their properties, limitations, theoretical principles and their prospective in tailoring appropriate micro-nanostructures for tissue regeneration applications. This review also includes discussion on recent works done in the field of tissue engineering.
科研通智能强力驱动
Strongly Powered by AbleSci AI