Thrombopoietin receptor is required for the oncogenic function of CALR mutants

PH performed the cell culture, genotyping and next-generation sequencing (NGS) experiments, interpreted the results and wrote the manuscript.ACM and SL collected clinical data and contributed in follow-up of the patient.RB coordinated HSC transplantation and contributed in the material collection.RT designed NGS assays.LS performed cytological and flow cytometry analysis of patient samples.DB and CM performed the standard molecular and chimerism analysis.