Zwitterionic polyurethane thin films enabling wet conformal adhesion to dynamic tissues

applications and, more importantly, promotes the formation of a hydration layer. This hydration layer would enable synergistic "liquid bridge" and "molecular bridge" effects that significantly enhance frictional interactions with wet tissue surfaces. In case studies, transferring ZWPU thin films onto edematous mouse brains and expanded rabbit lungs demonstrates unprecedented wet conformal adhesion to dynamic tissues, sustaining stretch ratios up to 150% without slippage or fracture. These findings establish ZWPU thin films as a promising material for implantable bioelectronics and advanced biointerfaces.