Automatic nodule detection for lung cancer in CT images: A review

Automatic lung nodule detection has great significance for treating lung cancer and increasing patient survival. This work summarizes a critical review of recent techniques for automatic lung nodule detection in computed tomography images. This review indicates the current tendency and obtained progress as well as future challenges in this field. This research covered the databases including Web of Science, PubMed, and the Press, including IEEE Xplore and Science Direct, up to May 2018. Each part of the paper is summarized carefully in terms of the method and validation results for better comparison. Based on the results, some techniques show better performance for lung nodule detection. However, researchers should pay attention to the existing challenges, such as high sensitivity with a low false positive rate, large and different patient databases, developing or optimizing the detection technique of various types of lung nodules with different sizes, shapes, textures and locations, combining electronic medical records and picture archiving and communication systems, building efficient feature sets for better classification and promoting the cooperation and communication between academic institutions and medical organizations. We believe that automatic computer-aided detection systems will be developed with strong robustness, high efficiency and security assurance. This review will be helpful for professional researchers and radiologists to further learn about the latest techniques in computer-aided detection systems.