Quintupling Inhaled Glucocorticoids to Prevent Childhood Asthma Exacerbations

DJ Jackson, LB Bacharier, DT Mauger. N Engl J Med. 2018;375(10):891–901 To determine if an increased dose of inhaled glucocorticoid (ICS) will prevent the progression to asthma exacerbation. The study included 254 children, 5 to 11 years of age, with mild to moderate persistent asthma who had at least 1 exacerbation treated with systemic glucocorticoids in the …